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Quellenverzeichnis

Jede Wirkaussage in diesem Portal trägt mindestens eine Quellenangabe. Hier stehen alle Belege gesammelt: 408 Quellen, 656 Zitate in 32 Substanz-Beiträgen. Gleiche DOI oder gleicher PMID bedeutet dieselbe Quelle, auch wenn zwei Beiträge sie getrennt zitieren.

Quellen

408

Zitate

656

mit PMID

300

mit DOI

299

nur amtliche URL

Erfahrungsberichte

408 von 408

2026 § 13 Arzneimittelgesetz: Herstellung von Arzneimitteln

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: Epithalon,MOTS-c,NAD+,SS-31 (Elamipretide)
2026 § 2 AntiDopG: Unerlaubter Umgang mit Dopingmitteln

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: AOD-9604,BPC-157 + TB-500,TB-500
2026 § 2 Arzneimittelgesetz: Arzneimittelbegriff

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: 5-Amino-1MQ,AHK-Cu,AOD-9604,BPC-157,BPC-157 + TB-500,CJC-1295 (No DAC),CJC-1295 + Ipamorelin,DSIP,Epithalon,GHK-Cu,GLOW Blend,Glutathion (GSH),Ipamorelin,KLOW Blend,KPV,Melanotan II,MOTS-c,N-Acetyl Semax,NAD+,Pinealon,Selank,Semax,Sermorelin,SS-31 (Elamipretide),TB-500,Tesamorelin,Tesamorelin + Ipamorelin,Thymosin Alpha-1,Tripple-G
2026 § 21 Arzneimittelgesetz: Zulassungspflicht

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: 5-Amino-1MQ,AHK-Cu,AOD-9604,BPC-157,Cagrilintide,CJC-1295 (No DAC),CJC-1295 + Ipamorelin,Epithalon,GHK-Cu,GLOW Blend,Glutathion (GSH),Ipamorelin,KLOW Blend,Melanotan II,MOTS-c,N-Acetyl Semax,NAD+,Selank,Semaglutide,Semax,Sermorelin,SS-31 (Elamipretide),Tesamorelin,Tesamorelin + Ipamorelin,Tirzepatide,Tripple-G
2026 § 43 Arzneimittelgesetz: Apothekenpflicht

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: Glutathion (GSH),NAD+,Semaglutide,Tirzepatide
2026 § 48 Arzneimittelgesetz: Verschreibungspflicht

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: Glutathion (GSH),NAD+
2026 § 5 Arzneimittelgesetz: Verbot bedenklicher Arzneimittel

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: Glutathion (GSH),Ipamorelin
2026 § 6 AntiDopG mit Anlage (Verbot bestimmter Stoffe und Methoden)

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: BPC-157,CJC-1295 (No DAC),Epithalon,Ipamorelin,Sermorelin,Tesamorelin
2026 § 73 Arzneimittelgesetz: Verbringungsverbot

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: 5-Amino-1MQ,Cagrilintide,Semaglutide,Tirzepatide,Tripple-G
2026 21 CFR 314.126: Adequate and well-controlled studies

Electronic Code of Federal Regulations

Behörde zitiert in: SS-31 (Elamipretide)
2026 21 CFR 314.510: Approval based on a surrogate endpoint or on an effect on a clinical endpoint other than survival or irreversible morbidity

Electronic Code of Federal Regulations

Behörde zitiert in: SS-31 (Elamipretide)
2026 A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight (REDEFINE 1)

ClinicalTrials.gov, NCT05567796

Datenbank zitiert in: Cagrilintide
2026 A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight (REDEFINE 2)

ClinicalTrials.gov, NCT05394519

Datenbank zitiert in: Cagrilintide
2026 A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity (TRIUMPH-5)

ClinicalTrials.gov

Datenbank zitiert in: Tripple-G
2026 A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight (TRIUMPH-1)

ClinicalTrials.gov

Datenbank zitiert in: Tripple-G
2026 A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease (TRIUMPH-3)

ClinicalTrials.gov

Datenbank zitiert in: Tripple-G
2026 A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight (TRIUMPH-2)

ClinicalTrials.gov

Datenbank zitiert in: Tripple-G
2026 A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Knee Osteoarthritis (TRIUMPH-4)

ClinicalTrials.gov

Datenbank zitiert in: Tripple-G
2026 A Targeted Metabolomic Assessment of Oral Glutathione Bioavailability and Safety in Humans: A Randomized Crossover Clinical Trial

Solnier J, Du M, Zhang Y, et al..Antioxidants · PMID 41897500

RCT zitiert in: Glutathion (GSH)
2026 Analyzing the impact of subcutaneous injection needle, device, and administration characteristics on patient outcomes

Drug Delivery

Übersicht zitiert in: Insulinspritzen
2026 Anlage zu § 6 AntiDopG (Verbot bestimmter Stoffe und Methoden)

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: 5-Amino-1MQ,AOD-9604,BPC-157 + TB-500,Cagrilintide,CJC-1295 (No DAC),CJC-1295 + Ipamorelin,Ipamorelin,MOTS-c,Sermorelin,TB-500,Tesamorelin,Tesamorelin + Ipamorelin,Tirzepatide,Tripple-G
2026 BfArM warnt vor Risiken von Drip-Spa-Infusionen, Pressemitteilung Nr. 04/26 vom 12. Mai 2026

Bundesinstitut für Arzneimittel und Medizinprodukte.BfArM

Behörde zitiert in: Glutathion (GSH),NAD+
2026 Bulk Drug Substances Used in Compounding

U.S. Food and Drug Administration

Behörde zitiert in: 5-Amino-1MQ,AOD-9604,BPC-157,Cagrilintide,Tirzepatide,Tripple-G
2026 Bulk Drug Substances Used in Compounding Under Section 503A of the FD&C Act

U.S. Food and Drug Administration

Behörde zitiert in: BPC-157 + TB-500,CJC-1295 (No DAC),Epithalon,KPV,MOTS-c,NAD+,TB-500,Tesamorelin
2026 Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks

U.S. Food and Drug Administration.FDA

Behörde zitiert in: AHK-Cu,CJC-1295 (No DAC),CJC-1295 + Ipamorelin,DSIP,Epithalon,GHK-Cu,GLOW Blend,Ipamorelin,KLOW Blend,Melanotan II,MOTS-c,N-Acetyl Semax,NAD+,Pinealon,Selank,Semax,Tesamorelin + Ipamorelin
2026 ClinicalTrials.gov, Suche „ipamorelin AND CJC-1295“ (API v2, Abfrage am 14.09.2026)

U.S. National Library of Medicine

Datenbank zitiert in: CJC-1295 + Ipamorelin
2026 ClinicalTrials.gov, Suche „ipamorelin AND tesamorelin“ (API v2, Abfrage am 14.09.2026)

U.S. National Library of Medicine

Datenbank zitiert in: Tesamorelin + Ipamorelin
2026 ClinicalTrials.gov: Registereinträge NCT02867267 (TESTS) und NCT00711620 (ETASS)

U.S. National Library of Medicine

Datenbank zitiert in: Thymosin Alpha-1
2026 Delta sleep-inducing peptide, CID 68816

PubChem, National Library of Medicine

Datenbank zitiert in: DSIP
2026 Dose-Dependent Angiogenic Effects of Intravenous Nicotinamide Riboside in Mice with a Lewis Lung Carcinoma Model

Podyacheva E, et al..Bulletin of Experimental Biology and Medicine · PMID 42509435

Tier zitiert in: NAD+
2026 Drugs@FDA: Abfrage der offenen FDA-Schnittstelle zu Thymalfasin, Zadaxin und Thymosin (keine Treffer)

U.S. Food and Drug Administration, openFDA

Behörde zitiert in: Thymosin Alpha-1
2026 Drugs@FDA: BLA 022505 (Egrifta, Tesamorelin), Originalzulassung 10.11.2010, Inhaber Theratechnologies

U.S. Food and Drug Administration

Behörde zitiert in: Tesamorelin,Tesamorelin + Ipamorelin
2026 Drugs@FDA: NDA 019863, Geref Diagnostic (sermorelin acetate) Injection, EMD Serono

U.S. Food and Drug Administration

Behörde zitiert in: Sermorelin
2026 Drugs@FDA: NDA 020443, Geref (sermorelin acetate) 0,5 mg/Vial und 1 mg/Vial, EMD Serono

U.S. Food and Drug Administration

Behörde zitiert in: Sermorelin
2026 Effect of Nicotinamide Adenine Dinucleotide on Heart Failure Caused by Ischemic Cardiomyopathy: A Randomized, Placebo-Controlled Trial

Yu X, Xu J, Cao J, et al..American Journal of Cardiovascular Drugs · PMID 40954388

RCT zitiert in: NAD+
2026 Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)

ClinicalTrials.gov

Datenbank zitiert in: Tripple-G
2026 Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study

Biçer O, Adanir O, Güleryüz Y, et al..Joint Diseases and Related Surgery · PMID 42542926

Tier zitiert in: BPC-157 + TB-500,TB-500
2026 Efficacy and safety of co-administered cagrilintide and semaglutide versus semaglutide alone in adults with overweight or obesity with or without type 2 diabetes in Japan and Taiwan (REDEFINE 5): a multicentre, randomised, active-controlled, phase 3a trial

Yamauchi T, Becker NP, Hagemann CA, Huang KC, et al..The Lancet Diabetes & Endocrinology · PMID 42009015

RCT zitiert in: Cagrilintide
2026 Efficacy and safety of retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in people with type 2 diabetes and inadequate glycaemic control with diet and exercise (TRANSCEND-T2D-1): a double-blind, randomised, phase 3 trial

Bajaj HS, Welch M, Shah P, Luna E, et al..The Lancet · PMID 42250575

RCT zitiert in: Tripple-G
2026 Efficacy and Safety of Tesamorelin in People Living With HIV (PLWH) With Lipodystrophy: A Systematic Review and Meta-Analysis

Ditta AM, Naeem RM, Sami MM, Abdul Rafey M, Ali H, Amjad MW, Jahangir F, Rizvi KA, Mohammad F, Abu Dawood H, Suleman M, Saddique MN.Journal of the International Association of Providers of AIDS Care · PMID 42538058

Meta zitiert in: Tesamorelin
2026 EGRIFTA SV (Tesamorelin) for injection: Prescribing Information

Theratechnologies Inc..U.S. Food and Drug Administration, DailyMed

Behörde zitiert in: Ipamorelin,Tesamorelin
2026 EGRIFTA SV (Tesamorelin): Fachinformation, Abschnitte 2, 5, 6, 7 und 12.3

U.S. Food and Drug Administration, DailyMed

Behörde zitiert in: Tesamorelin + Ipamorelin
2026 FDA Briefing Document, Pharmacy Compounding Advisory Committee: KPV-Related Bulk Drug Substances (KPV (Free Base) and KPV acetate)

U.S. Food and Drug Administration, Center for Drug Evaluation and Research.U.S. Food and Drug Administration

Behörde zitiert in: KPV
2026 FDA Briefing Document, Pharmacy Compounding Advisory Committee: TB-500-Related Bulk Drug Substances

U.S. Food and Drug Administration, Center for Drug Evaluation and Research

Behörde zitiert in: BPC-157 + TB-500,TB-500
2026 FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss

U.S. Food and Drug Administration

Behörde zitiert in: 5-Amino-1MQ,Cagrilintide,Semaglutide,Tirzepatide,Tripple-G
2026 Gesetz über die berufsmäßige Ausübung der Heilkunde ohne Bestallung (Heilpraktikergesetz)

Bundesministerium der Justiz, gesetze-im-internet.de

Behörde zitiert in: Glutathion (GSH),NAD+
2026 Intravenous infusion of nicotinamide adenine dinucleotide (NAD+) versus nicotinamide riboside (NR): a retrospective tolerability pilot study in a real-world setting

Reyna K, Heinzen G, Patel N, Ritter M, Siojo A, Legere H, Pojednic R.Frontiers in Aging · PMID 41704678

Sonstiges zitiert in: NAD+
2026 July 23-24, 2026: Meeting of the Pharmacy Compounding Advisory Committee

U.S. Food and Drug Administration

Behörde zitiert in: BPC-157 + TB-500,KPV,MOTS-c,TB-500
2026 Lean Mass Changes With Incretin Therapy Versus Lifestyle Intervention: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

Eisa N, Barood O.Diabetes, Obesity and Metabolism · PMID 41877354

Meta zitiert in: Tirzepatide
2026 Lilly’s triple agonist, retatrutide, delivered powerful weight loss in pivotal phase 3 obesity trial

Eli Lilly and Company, Pressemitteilung vom 21. Mai 2026

Sonstiges zitiert in: Tripple-G
2026 Melanotan II tanning peptide products found to be inconsistently dosed (Safety Alert vom 17.08.2026)

Therapeutic Goods Administration.TGA (Australien)

Behörde zitiert in: Melanotan II
2026 MOTS-c improves intrinsic muscle mitochondrial bioenergetic health and efficiency in a PGC-1α/AMPK-dependent manner

Gudiksen A, Hansen CC, van der Stede T, et al..Free Radical Biology and Medicine · PMID 41520850

Tier zitiert in: MOTS-c
2026 Mounjaro: Product Information (Zusammenfassung der Merkmale des Arzneimittels)

European Medicines Agency, EPAR

Behörde zitiert in: Tirzepatide
2026 NAD und NMN in Nahrungsergänzungsmitteln: Was ist erlaubt?

Verbraucherzentrale Hessen.Verbraucherzentrale Hessen

Datenbank zitiert in: NAD+
2026 NAD+ biology and supplementation: From mechanisms to clinical perspectives

Pandolfi S, Ghezzi C, Björklund G, Metalla M, Paone FM, Chirumbolo S.Molecular Biology Reports · PMID 42489969

Übersicht zitiert in: NAD+
2026 NAD+ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidence

Gallagher C, Emmanuel OO.Ageing Research Reviews · PMID 41655607

Meta zitiert in: NAD+
2026 Narrative review of intravenous NAD+ and NAD+ precursors in wellness and translational medicine

Alangari A, Arif J, Al Qureshah F, Alkhodairy F.Frontiers in Aging

Übersicht zitiert in: NAD+
2026 NCT07505745: MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity (MOTS-MET)

ClinicalTrials.gov, Studienregistrierung

Datenbank zitiert in: MOTS-c
2026 NCT07531251: Bestätigungsstudie zu Forzinity bei Barth-Syndrom

ClinicalTrials.gov, Studienregistrierung

Datenbank zitiert in: SS-31 (Elamipretide)
2026 openFDA, Datenbank der Arzneimittelrückrufe (drug/enforcement), Suchbegriff „nicotinamide adenine dinucleotide“

U.S. Food and Drug Administration, offene Datenschnittstelle

Datenbank zitiert in: NAD+
2026 Ozempic: EPAR und Produktinformation

European Medicines Agency

Behörde zitiert in: Semaglutide
2026 Pen Needle Reuse in People with Diabetes Who Inject Insulin: A Narrative Review

Diabetes Therapy

Übersicht zitiert in: Insulinspritzen
2026 Pharmacy Compounding Advisory Committee; Notice of Meeting (Docket FDA-2025-N-6895)

Federal Register, Bekanntmachung vom 16. April 2026

Behörde zitiert in: Epithalon
2026 Pharmacy Compounding Advisory Committee: Briefing Document for BPC-157-Related Bulk Drug Substances

U.S. Food and Drug Administration

Behörde zitiert in: BPC-157,BPC-157 + TB-500
2026 Pinealon, CID 10273502

PubChem, National Library of Medicine

Datenbank zitiert in: Pinealon
2026 PubChem Compound 66522933: 1-methylquinolin-1-ium-5-amine iodide

National Center for Biotechnology Information, PubChem

Datenbank zitiert in: 5-Amino-1MQ
2026 PubChem Compound 950107: 5-Amino-1-methylquinolinium

National Center for Biotechnology Information, PubChem

Datenbank zitiert in: 5-Amino-1MQ
2026 PubChem Compound CID 172638603: N-acetyl semax / N-acetyl semax amidate

PubChem, National Library of Medicine

Datenbank zitiert in: N-Acetyl Semax
2026 PubChem Compound CID 9811102: Semax

PubChem, National Library of Medicine

Datenbank zitiert in: N-Acetyl Semax
2026 REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels

ClinicalTrials.gov, NCT05669755

Datenbank zitiert in: Cagrilintide
2026 Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials

Giblin K, Kaplan LM, Somers VK, Le Roux CW, et al..Diabetes, Obesity and Metabolism · PMID 41090431

Sonstiges zitiert in: Tripple-G
2026 Rybelsus: EPAR und Produktinformation

European Medicines Agency

Behörde zitiert in: Semaglutide
2026 Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance

Mendias CL, Awan TM.Sports Medicine · PMID 41966639

Übersicht zitiert in: AOD-9604,BPC-157 + TB-500,MOTS-c
2026 Safety of beta-nicotinamide mononucleotide (β-NMN) pursuant the regulation (EU) 2015/2283 and the bioavailability of nicotinamide from this source in the context of Directive 2002/46/EC

EFSA Panel on Nutrition, Novel Foods and Food Allergens.EFSA Journal · PMID 42125559

Behörde zitiert in: NAD+
2026 Safety of S-acetyl glutathione as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Panel on Nutrition, Novel Foods and Food Allergens.EFSA Journal · PMID 42683004

Behörde zitiert in: Glutathion (GSH)
2026 Scenesse (Afamelanotid): Zulassung und Produktinformation

Europäische Arzneimittel-Agentur.EMA

Behörde zitiert in: Melanotan II
2026 Sermorelin, CID 16132413

PubChem, National Library of Medicine

Datenbank zitiert in: Sermorelin
2026 Sitzungsunterlage des Pharmacy Compounding Advisory Committee zu MOTS-c bezogenen Bulk-Arzneimittelstoffen

U.S. Food and Drug Administration.U.S. Food and Drug Administration, Sitzungsunterlage zum Docket FDA-2025-N-6895

Behörde zitiert in: MOTS-c
2026 Systemic MOTS-c levels are increased in adults with obesity in association with metabolic dysregulation and remain unchanged after weight loss

Yoon SH, Yuan F, Zhu X, et al..Journal of Clinical and Translational Endocrinology · PMID 41551324

Sonstiges zitiert in: MOTS-c
2026 The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration

Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, Ruchała M.Frontiers in Endocrinology · PMID 42395176

Übersicht zitiert in: CJC-1295 (No DAC),CJC-1295 + Ipamorelin,Ipamorelin,Sermorelin,Tesamorelin,Tesamorelin + Ipamorelin
2026 Therapeutic peptides in gerontology: mechanisms and applications for healthy aging

Mavrych V, Shypilova I, Bolgova O.Frontiers in Aging · PMID 42021992

Übersicht zitiert in: Epithalon,Pinealon
2026 Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions

Rahman OF, Lee SJ, Seeds WA.JAAOS Global Research & Reviews · PMID 41490200

Übersicht zitiert in: AOD-9604
2026 Thymosin-ɑ1 for people with chronic hepatitis B

Naing C, Ni H, Aung HH, et al..Cochrane Database of Systematic Reviews · PMID 42713852

Meta zitiert in: Thymosin Alpha-1
2026 Vitamin B3 derivatives support pancreatic cancer cell survival and chemotherapy resistance

Cancer Letters · PMID 41724424

In vitro zitiert in: NAD+
2026 WADA Prohibited List 2026, Kategorie S2 Nummer S2.2.4

World Anti-Doping Agency

Behörde zitiert in: CJC-1295 (No DAC),Ipamorelin,Sermorelin,Tesamorelin
2026 WADA Prohibited List, Kategorie S0: Non-Approved Substances

World Anti-Doping Agency

Behörde zitiert in: 5-Amino-1MQ,AHK-Cu,AOD-9604,BPC-157,BPC-157 + TB-500,CJC-1295 + Ipamorelin,Epithalon,GHK-Cu,GLOW Blend,Glutathion (GSH),KLOW Blend,KPV,Melanotan II,MOTS-c,N-Acetyl Semax,NAD+,Pinealon,Selank,Semax,SS-31 (Elamipretide),TB-500,Tesamorelin + Ipamorelin,Thymosin Alpha-1,Tripple-G
2026 Wegovy: Product Information (Zusammenfassung der Merkmale des Arzneimittels)

European Medicines Agency, EPAR

Behörde zitiert in: Semaglutide,Tripple-G
2025 Antisepsis before skin injections: does the WHO recommendation for washing, instead alcohol-based antisepsis, hold up?

GMS Hygiene and Infection Control

Übersicht zitiert in: Alkoholtupfer
2025 Bacteriostatic Sodium Chloride Injection: Produktinformation (Benzylalkohol 0,9 % als Konservierungsmittel)

DailyMed, U.S. National Library of Medicine

Behörde zitiert in: Bakteriostatisches Wasser
2025 Cagrilintide-Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes

Davies MJ, Bajaj HS, Broholm C, Eliasen A, et al..New England Journal of Medicine · PMID 40544432

RCT zitiert in: Cagrilintide
2025 Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes

Nicholls SJ, Pavo I, Bhatt DL, Buse JB, et al..New England Journal of Medicine · PMID 41406444

RCT zitiert in: Tirzepatide
2025 Citizen Petition Response zu Docket FDA-2023-P-0872: Regulatory Status of Beta-Nicotinamide Mononucleotide (NMN)

U.S. Food and Drug Administration.U.S. Food and Drug Administration, Antwortschreiben vom 29. September 2025

Behörde zitiert in: NAD+
2025 Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity

Garvey WT, Blüher M, Osorto Contreras CK, Davies MJ, et al..New England Journal of Medicine · PMID 40544433

RCT zitiert in: Cagrilintide
2025 Declaratory Order: Resolution of Shortages of Semaglutide Injection Products

U.S. Food and Drug Administration, Dokument vom 21. Februar 2025

Behörde zitiert in: Semaglutide
2025 Diabetes Technology: Standards of Care in Diabetes 2025

Diabetes Care (American Diabetes Association)

Leitlinie zitiert in: Insulinspritzen
2025 Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial

Coskun T, Wu Q, Schloot NC, Haupt A, et al..The Lancet Diabetes & Endocrinology · PMID 40609566

RCT zitiert in: Tripple-G
2025 Effects of TA-65 on telomere length, functional outcomes, and inflammation: a systematic review and meta-analysis

Su X, Wang C, Gou Z, et al..Cell Biology and Toxicology · PMID 41286474

Meta zitiert in: Epithalon
2025 Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review

Vasireddi N, Hahamyan H, Salata MJ, Karns M, Calcei JG, Voos JE, Apostolakos JM.HSS Journal · PMID 40756949

Meta zitiert in: BPC-157,BPC-157 + TB-500,GLOW Blend,KLOW Blend
2025 Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity

Al-Dulaimi S, Thomas R, Matta S, Roberts T.Biogerontology · PMID 40908429

In vitro zitiert in: Epithalon
2025 FDA Grants Accelerated Approval to First Treatment for Barth Syndrome

U.S. Food and Drug Administration, Pressemitteilung vom 19. September 2025

Behörde zitiert in: SS-31 (Elamipretide)
2025 FORZINITY (elamipretide) Injektionslösung: Produktinformation (Label), SPL-ID 146bf34c-76f2-48db-ac07-fb29cce2cd75

Stealth BioTherapeutics Inc..U.S. Food and Drug Administration, zugelassene Produktinformation, Stand 10. Dezember 2025

Behörde zitiert in: SS-31 (Elamipretide)
2025 Glutathione as a skin-lightening agent and in melasma: a systematic review

Sarkar R, et al..International Journal of Dermatology · PMID 39444151

Meta zitiert in: Glutathion (GSH)
2025 Hygienepraktiken in Peptid-Communities

Nutzerforen

Anekdote zitiert in: Alkoholtupfer,Bakteriostatisches Wasser,BPC-157,BPC-157 + TB-500,CJC-1295 (No DAC),Insulinspritzen,Ipamorelin,KPV,TB-500,Thymosin Alpha-1
2025 Intravenous Glutathione and Vitamin Supplementation Causing Stevens-Johnson Syndrome: A Case Report

Johnson JS, Jarvis NR, Martinez AM, et al..Journal of Burn Care and Research · PMID 40057759

Fallbericht zitiert in: Glutathion (GSH)
2025 Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes

Kong BS, et al..Experimental and Molecular Medicine · PMID 40855115

Tier zitiert in: MOTS-c
2025 NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity

Heide J, Bilecz AJ, Patnaik S, Allega MF, et al..Nature · PMID 40702186

Tier zitiert in: 5-Amino-1MQ
2025 Novo Nordisk files for FDA approval of CagriSema, the first once-weekly combination of GLP-1 and amylin analogues for weight management

Novo Nordisk, Pressemitteilung vom 18. Dezember 2025

Sonstiges zitiert in: Cagrilintide
2025 Nurses' Attitudes and Clinical Judgment on Skin Disinfection Before Subcutaneous Injection

Nursing Reports

Sonstiges zitiert in: Alkoholtupfer
2025 Oral MIB-626 (β Nicotinamide Mononucleotide) Safely Raises Blood Nicotinamide Adenine Dinucleotide Levels in Hospitalized Patients With COVID-19 and Acute Kidney Injury: A Randomized Controlled Trial

Pencina KM, Leaf DE, Valderrabano RJ, et al..FASEB BioAdvances · PMID 40746868

RCT zitiert in: NAD+
2025 Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes

McGuire DK, Marx N, Mulvagh SL, Deanfield JE, et al..New England Journal of Medicine · PMID 40162642

RCT zitiert in: Semaglutide
2025 Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity

Wharton S, Lingvay I, Bogdanski P, Duque do Vale R, et al..New England Journal of Medicine · PMID 40934115

RCT zitiert in: Semaglutide
2025 Overview of Epitalon: Highly Bioactive Pineal Tetrapeptide with Promising Properties

Araj SK, Brzezik J, Mądra-Gackowska K, Szeleszczuk Ł.International Journal of Molecular Sciences · PMID 40141333

Übersicht zitiert in: Epithalon,Pinealon
2025 PRAC concludes eye condition NAION is a very rare side effect of semaglutide medicines Ozempic, Rybelsus and Wegovy

European Medicines Agency, Sicherheitsmitteilung des PRAC

Behörde zitiert in: Semaglutide
2025 ReCLAIM-2: A Randomized Phase II Clinical Trial Evaluating Elamipretide in Age-related Macular Degeneration, Geographic Atrophy Growth, Visual Function, and Ellipsoid Zone Preservation

Ehlers JP, Yeh S, Cakir B, et al..Ophthalmology Science · PMID 39605874

RCT zitiert in: SS-31 (Elamipretide)
2025 Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing

McGuire FP, et al..Current Reviews in Musculoskeletal Medicine · PMID 40789979

Übersicht zitiert in: BPC-157
2025 Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.

Liu R, Chen Y, Huang H, et al..British Journal of Pharmacology · PMID 40692165

Tier zitiert in: Semax
2025 Systemic Inflammatory Response Syndrome Following High-Dose Intravenous Glutathione-Containing Revitalising Solution in a Patient on Tirzepatide: A Case Report

Sharma D, Daram S, Sharma P.Cureus · PMID 40556995

Fallbericht zitiert in: Glutathion (GSH)
2025 The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta-Analysis

Prokopidis K, Moriarty F, Bahat G, et al..Journal of Cachexia, Sarcopenia and Muscle · PMID 40275690

Meta zitiert in: NAD+
2025 The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial

Wu J, Pei F, Zhou L, et al..BMJ · PMID 39814420

RCT zitiert in: Thymosin Alpha-1
2025 Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity

Packer M, Zile MR, Kramer CM, Baum SJ, et al..New England Journal of Medicine · PMID 39555826

RCT zitiert in: Tirzepatide
2025 Tirzepatide for Obesity Treatment and Diabetes Prevention

Jastreboff AM, le Roux CW, Stefanski A, Aronne LJ, et al..New England Journal of Medicine · PMID 39536238

RCT zitiert in: Tirzepatide
2025 Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective

Mortazavi SM, Mohammadi Vadoud SA, Moghimi HR.BioImpacts · PMID 39963574

Übersicht zitiert in: AHK-Cu,GHK-Cu
2025 US Food and Drug Administration Approval Summary: Imetelstat for Selected Patients With Low- to Intermediate-1 Risk Myelodysplastic Syndromes With Transfusion-Dependent Anemia

Kim N, Pulte ED, Ehrlich LA, et al..Journal of Clinical Oncology · PMID 41135032

Behörde zitiert in: Epithalon
2025 Государственный реестр лекарственных средств: Семакс® (Semax), Nasentropfen 0,1 %, Рег. Nr. ЛП-№(009449)-(РГ-RU)

Ministerium für Gesundheit der Russischen Föderation, grls.rosminzdrav.ru

Behörde zitiert in: N-Acetyl Semax,Selank,Semax
2025 Селанк® (Selank), Nasentropfen 0,15 %: Beschreibung des Wirkstoffs mit Registrierungsnummer und Fachinformation

Vidal, russischer Arzneimittelkatalog

Datenbank zitiert in: Selank
2024 A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment

Orr ME, Kotkowski E, Ramirez P, et al..GeroScience · PMID 37994989

RCT zitiert in: NAD+
2024 Amylin, Another Important Neuroendocrine Hormone for the Treatment of Diabesity

Eržen S, Tonin G, Jurišić Eržen D, Klen J.International Journal of Molecular Sciences · PMID 38338796

Übersicht zitiert in: Cagrilintide
2024 CagriSema demonstrates superior weight loss in adults with obesity or overweight in the REDEFINE 1 trial

Novo Nordisk, Pressemitteilung vom 20. Dezember 2024

Sonstiges zitiert in: Cagrilintide
2024 Effects of once-weekly subcutaneous retatrutide on weight and metabolic markers: A systematic review and meta-analysis of randomized controlled trials

Pasqualotto E, Ferreira ROM, Chavez MP, Hohl A, et al..Metabolism Open · PMID 39318607

Meta zitiert in: Tripple-G
2024 Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes

Perkovic V, Tuttle KR, Rossing P, Mahaffey KW, et al..New England Journal of Medicine · PMID 38785209

RCT zitiert in: Semaglutide
2024 Elamipretide Topical Ophthalmic Solution for the Treatment of Subjects with Leber Hereditary Optic Neuropathy: A Randomized Trial

Karanjia R, Sadun AA, Chen MY, et al..Ophthalmology · PMID 37923251

RCT zitiert in: SS-31 (Elamipretide)
2024 Exploring NNMT: from metabolic pathways to therapeutic targets

Park J, Shin EJ, Kim TH, Yang JH, et al..Archives of Pharmacal Research · PMID 39604638

Übersicht zitiert in: 5-Amino-1MQ
2024 FDA Approves First Medication for Obstructive Sleep Apnea

U.S. Food and Drug Administration, Pressemitteilung vom 20. Dezember 2024

Behörde zitiert in: Tirzepatide
2024 FDA Briefing Document, Pharmacy Compounding Advisory Committee: AOD-9604-Related Bulk Drug Substances

U.S. Food and Drug Administration, Dokument vom 4. Dezember 2024

Behörde zitiert in: AOD-9604
2024 FDA reminds compounders to use ingredients suitable for sterile compounding

U.S. Food and Drug Administration, Compounding Risk Alert

Behörde zitiert in: NAD+
2024 Genotype-specific effects of elamipretide in patients with primary mitochondrial myopathy: a post hoc analysis of the MMPOWER-3 trial

Karaa A, Bertini E, Carelli V, et al..Orphanet Journal of Rare Diseases · PMID 39574155

RCT zitiert in: SS-31 (Elamipretide)
2024 Long-term efficacy and safety of elamipretide in patients with Barth syndrome: 168-week open-label extension results of TAZPOWER

Thompson WR, Manuel R, Abbruscato A, et al..Genetics in Medicine · PMID 38602181

Sonstiges zitiert in: SS-31 (Elamipretide)
2024 Long-Term Stability of Nicotinamide Cofactors in Common Aqueous Buffers: Implications for Cell-Free Biocatalysis

Wolfe KD, Alahuhta M, Himmel ME, Bomble YJ, Jennings GK, Cliffel DE.Molecules · PMID 39598842

In vitro zitiert in: NAD+
2024 Making bloodwork work: the impact of sample collection, processing, and storage on plasma glutathione measurement, and implications for translation

Coden KM, Nguyen DKK, Moorhead R, et al..Translational Psychiatry · PMID 39313523

Sonstiges zitiert in: Glutathion (GSH)
2024 Meeting highlights from the Pharmacovigilance Risk Assessment Committee (PRAC) 8-11 April 2024

European Medicines Agency

Behörde zitiert in: Semaglutide
2024 Multifactor Quality and Safety Analysis of Semaglutide Products Sold by Online Sellers Without a Prescription: Market Surveillance, Content Analysis, and Product Purchase Evaluation Study

Ashraf AR, Mackey TK, Vida RG, et al..Journal of Medical Internet Research · PMID 39509151

Sonstiges zitiert in: BPC-157 + TB-500
2024 NCT05162768: nuPOWER, Elamipretide bei myopathischem mitochondrialem Depletionssyndrom

ClinicalTrials.gov, Studienregistrierung

Datenbank zitiert in: SS-31 (Elamipretide)
2024 Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction

Babula JJ, Bui D, Stevenson HL, Watowich SJ, et al..Diabetes, Obesity and Metabolism · PMID 39161060

Tier zitiert in: 5-Amino-1MQ
2024 Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial

McDermott MM, Martens CR, Domanchuk KJ, et al..Nature Communications · PMID 38871717

RCT zitiert in: NAD+
2024 Omission of alcohol skin cleansing and risk of adverse events in long-term care residents undergoing COVID-19 vaccination

Human Vaccines & Immunotherapeutics

RCT zitiert in: Alkoholtupfer,Insulinspritzen
2024 Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro

Rahaman KA, Muresan AR, Min H, et al..Journal of Chromatography B · PMID 38382158

In vitro zitiert in: BPC-157 + TB-500,TB-500
2024 The correlation between mitochondrial derived peptide (MDP) and metabolic states: a systematic review and meta-analysis

Zhou Q, Yin S, Lei X, et al..Diabetology and Metabolic Syndrome · PMID 39160573

Meta zitiert in: MOTS-c
2024 Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity

Malhotra A, Grunstein RR, Fietze I, Weaver TE, et al..New England Journal of Medicine · PMID 38912654

RCT zitiert in: Tirzepatide
2024 Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial

Sanyal AJ, Kaplan LM, Frias JP, Brouwers B, et al..Nature Medicine · PMID 38858523

RCT zitiert in: Tripple-G
2023 A Pilot Trial of Thymalfasin (Thymosin-α-1) to Treat Hospitalized Patients With Hypoxemia and Lymphocytopenia Due to Coronavirus Disease 2019 Infection

Shehadeh F, Benitez G, Mylona EK, et al..The Journal of Infectious Diseases · PMID 36056913

RCT zitiert in: Thymosin Alpha-1
2023 Antimicrobial Preservatives for Protein and Peptide Formulations: An Overview

Pharmaceutics

Übersicht zitiert in: Bakteriostatisches Wasser
2023 Changes in levels of the antioxidant glutathione in brain and blood across the age span of healthy adults: A systematic review

Detcheverry F, Senthil S, Narayanan S, et al..NeuroImage: Clinical · PMID 37742519

Meta zitiert in: Glutathion (GSH)
2023 Designing Formulation Strategies for Enhanced Stability of Therapeutic Peptides in Aqueous Solutions: A Review

Nugrahadi PP, Hinrichs WLJ, Frijlink HW, et al..Pharmaceutics · PMID 36986796

Übersicht zitiert in: BPC-157 + TB-500
2023 Efficacy and safety of co-administered once-weekly cagrilintide 2·4 mg with once-weekly semaglutide 2·4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial

Frias JP, Deenadayalan S, Erichsen L, Knop FK, et al..The Lancet · PMID 37364590

RCT zitiert in: Cagrilintide
2023 Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial

Karaa A, Bertini E, Carelli V, et al..Neurology · PMID 37268435

RCT zitiert in: SS-31 (Elamipretide)
2023 Expertenkonsens zur klinischen Anwendung von Thymalfasin in der Infektiologie und Intensivmedizin (胸腺法新在感染和重症相关领域临床应用专家共识)

Chinesisches Journal für klinische Infektiologie (中华临床感染病杂志)

Leitlinie zitiert in: Thymosin Alpha-1
2023 FDA Approves New Medication for Chronic Weight Management

U.S. Food and Drug Administration, Pressemitteilung vom 8. November 2023

Behörde zitiert in: Tirzepatide
2023 NAD+ in Aging Biology: Potential Applications and Many Unknowns

Bhasin S, Seals D, Migaud M, et al..Endocrine Reviews · PMID 37364580

Übersicht zitiert in: NAD+
2023 Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study

Pencina KM, Valderrabano R, Wipper B, et al..The Journal of Clinical Endocrinology and Metabolism · PMID 36740954

RCT zitiert in: NAD+
2023 Nicotinamide Adenine Dinucleotide Precursor Suppresses Hepatocellular Cancer Progression in Mice

Pang J, et al..Nutrients · PMID 36986177

Tier zitiert in: NAD+
2023 NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson disease

Berven H, Kverneng S, Sheard E, et al..Nature Communications · PMID 38016950

RCT zitiert in: NAD+
2023 Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial

Knop FK, Aroda VR, do Vale RD, Holst-Hansen T, et al..The Lancet · PMID 37385278

RCT zitiert in: Semaglutide
2023 Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA

Rosenstock J, Frias J, Jastreboff AM, Du Y, et al..The Lancet · PMID 37385280

RCT zitiert in: Tripple-G
2023 Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes

Lincoff AM, Brown-Frandsen K, Colhoun HM, Deanfield J, et al..New England Journal of Medicine · PMID 37952131

RCT zitiert in: Semaglutide
2023 The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

Yi L, Maier AB, Tao R, et al..GeroScience · PMID 36482258

RCT zitiert in: NAD+
2023 The Emerging Roles of γ-Glutamyl Peptides Produced by γ-Glutamyltransferase and the Glutathione Synthesis System

Ikeda Y, Fujii J.Cells · PMID 38132151

Übersicht zitiert in: Glutathion (GSH)
2023 The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)

Pharaoh G, Kamat V, Kannan S, et al..GeroScience · PMID 37462785

Tier zitiert in: SS-31 (Elamipretide)
2023 Thymosin alpha1 use in adult COVID-19 patients: A systematic review and meta-analysis on clinical outcomes

Shang W, Zhang B, Ren Y, et al..International Immunopharmacology · PMID 36527881

Meta zitiert in: Thymosin Alpha-1
2023 Thymosin α1 and Its Role in Viral Infectious Diseases: The Mechanism and Clinical Application

Tao N, Xu X, Ying Y, et al..Molecules · PMID 37110771

Übersicht zitiert in: Thymosin Alpha-1
2023 Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial

Garvey WT, Frias JP, Jastreboff AM, le Roux CW, et al..The Lancet · PMID 37385275

RCT zitiert in: Tirzepatide
2023 Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial

Jastreboff AM, Kaplan LM, Frías JP, Wu Q, et al..New England Journal of Medicine · PMID 37366315

RCT zitiert in: Tripple-G
2023 USP General Chapter 797: Pharmaceutical Compounding, Sterile Preparations

United States Pharmacopeia

Behörde zitiert in: Alkoholtupfer,Bakteriostatisches Wasser
2022 EU/3/22/2614: Ausweisung als Arzneimittel für seltene Leiden, myopathisches mitochondriales Depletionssyndrom

Europäische Kommission, Beschluss C(2022) 3326 final

Behörde zitiert in: SS-31 (Elamipretide)
2022 Natural history comparison study to assess the efficacy of elamipretide in patients with Barth syndrome

Hornby B, Thompson WR, Manuel R, et al..Orphanet Journal of Rare Diseases · PMID 36056411

Sonstiges zitiert in: SS-31 (Elamipretide)
2022 Nicotinamide Mononucleotide Is Safely Metabolized and Significantly Reduces Blood Triglyceride Levels in Healthy Individuals

Kimura S, Ichikawa M, Sugawara S, et al..Cureus · PMID 36225528

Sonstiges zitiert in: NAD+
2022 Pentadecapeptide BPC 157 and the central nervous system

Vukojevic J, Milavic M, Perovic D, et al..Neural Regeneration Research · PMID 34380875

Übersicht zitiert in: BPC-157
2022 Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a cytoprotective pentadecapeptide, in rats and dogs

He L, Feng D, Guo H, et al..Frontiers in Pharmacology · PMID 36588717

Tier zitiert in: BPC-157
2022 Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice

Dimet-Wiley A, Wu Q, Wiley JT, Eswar A, et al..Scientific Reports · PMID 35013352

Tier zitiert in: 5-Amino-1MQ
2022 Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds

Mitchell W, Tamucci JD, Ng EA, et al..eLife · PMID 35913044

In vitro zitiert in: SS-31 (Elamipretide)
2022 The CD38 glycohydrolase and the NAD sink: implications for pathological conditions

Zeidler JD, Hogan KA, Agorrody G, et al..American Journal of Physiology. Cell Physiology · PMID 35138178

Übersicht zitiert in: NAD+
2022 Tirzepatide Once Weekly for the Treatment of Obesity

Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, et al..New England Journal of Medicine · PMID 35658024

RCT zitiert in: Tirzepatide
2021 A phase 2/3 randomized clinical trial followed by an open-label extension to evaluate the effectiveness of elamipretide in Barth syndrome, a genetic disorder of mitochondrial cardiolipin metabolism

Thompson WR, Manuel R, Abbruscato A, et al..Genetics in Medicine · PMID 33077895

RCT zitiert in: SS-31 (Elamipretide)
2021 Acute endurance exercise stimulates circulating levels of mitochondrial-derived peptides in humans

von Walden F, Fernandez-Gonzalo R, Norrbom J, et al..Journal of Applied Physiology · PMID 34351816

RCT zitiert in: MOTS-c
2021 Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

Sampson CM, Dimet AL, Neelakantan H, Ogunseye KO, et al..Scientific Reports · PMID 33707534

Tier zitiert in: 5-Amino-1MQ
2021 Effect of aerobic and resistance exercise on the mitochondrial peptide MOTS-c in Hispanic and Non-Hispanic White breast cancer survivors

Dieli-Conwright CM, Sami N, Norris MK, et al..Scientific Reports · PMID 34413391

RCT zitiert in: MOTS-c
2021 Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial

Rubino D, Abrahamsson N, Davies M, Hesse D, et al..JAMA · PMID 33755728

RCT zitiert in: Semaglutide
2021 EU/3/21/2430: Ausweisung als Arzneimittel für seltene Leiden, Barth-Syndrom

Europäische Kommission, Register der Ausweisungen für seltene Leiden

Behörde zitiert in: SS-31 (Elamipretide)
2021 Gazzetta Ufficiale: Änderungsanzeige zu ZADAXIN 1,6 mg/ml, A.I.C. 028364026, Inhaber Sciclone Pharmaceuticals Italy S.r.l.

Gazzetta Ufficiale della Repubblica Italiana, Parte Seconda n. 16

Behörde zitiert in: Thymosin Alpha-1
2021 In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial

Roshanravan B, Liu SZ, Ali AS, et al..PLOS ONE · PMID 34264994

RCT zitiert in: SS-31 (Elamipretide)
2021 LC-HRMS characterization of the skin pigmentation and sexual enhancers melanotan II and bremelanotide sold on the black market of performance and image enhancing drugs

Mestria S, Odoardi S, Frison G, Strano Rossi S.Drug Testing and Analysis · PMID 33245851

In vitro zitiert in: Melanotan II
2021 Melanotan II User Experience: A Qualitative Study of Online Discussion Forums

Gilhooley E, Daly S, O'Connor C, et al..Dermatology · PMID 34464955

Sonstiges zitiert in: Melanotan II
2021 Melanotan Tanning Injection: A Rare Cause of Priapism

Mallory CW, Lopategui DM, Cordon BH.Sexual Medicine · PMID 33460908

Fallbericht zitiert in: Melanotan II
2021 Mitochondrial-derived peptides and exercise

Woodhead JST, Merry TL.Biochimica et Biophysica Acta. General Subjects · PMID 34520826

Übersicht zitiert in: MOTS-c
2021 MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis

Reynolds JC, Lai RW, Woodhead JST, et al..Nature Communications · PMID 33473109

Tier zitiert in: MOTS-c
2021 MOTS-c reduces myostatin and muscle atrophy signaling

Kumagai H, Coelho AR, Wan J, et al..American Journal of Physiology. Endocrinology and Metabolism · PMID 33554779

Tier zitiert in: MOTS-c
2021 Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women

Yoshino M, Yoshino J, Kayser BD, et al..Science · PMID 33888596

RCT zitiert in: NAD+
2021 Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial

Lau DCW, Erichsen L, Francisco AM, Satylganova A, et al..The Lancet · PMID 34798060

RCT zitiert in: Cagrilintide
2021 Once-Weekly Semaglutide in Adults with Overweight or Obesity

Wilding JPH, Batterham RL, Calanna S, Davies M, et al..New England Journal of Medicine · PMID 33567185

RCT zitiert in: Semaglutide
2021 Plasma mitochondrial derived peptides MOTS-c and SHLP2 positively associate with android and liver fat in people without diabetes

Sequeira IR, Woodhead JST, Ogawa E, et al..Biochimica et Biophysica Acta. General Subjects · PMID 34419510

Sonstiges zitiert in: MOTS-c
2021 Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2·4 mg for weight management: a randomised, controlled, phase 1b trial

Enebo LB, Berthelsen KK, Kankam M, Lund MT, et al..The Lancet · PMID 33894838

RCT zitiert in: Cagrilintide
2021 Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.

Doyno CR, White CM.Journal of Clinical Pharmacology · PMID 34396551

Übersicht zitiert in: Selank
2021 Self-Cross-Linked Hydrogel of Cysteamine-Grafted γ-Polyglutamic Acid Stabilized Tripeptide KPV for Alleviating TNBS-Induced Ulcerative Colitis in Rats

Sun J, Xue P, Liu J, et al..ACS Biomaterials Science and Engineering · PMID 34547895

Tier zitiert in: KPV
2021 Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial

Davies M, Færch L, Jeppesen OK, Pakseresht A, et al..The Lancet · PMID 33667417

RCT zitiert in: Semaglutide
2021 Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells

Akar S, Duran T, Azzawri AA, Koçak N, et al..Journal of Obstetrics and Gynaecology · PMID 33645410

In vitro zitiert in: 5-Amino-1MQ
2021 Stable Gastric Pentadecapeptide BPC 157 and Wound Healing

Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, et al..Frontiers in Pharmacology · PMID 34267654

Übersicht zitiert in: BPC-157
2021 The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial

Søndergård SD, Cintin I, Kuhlman AB, et al..Applied Physiology, Nutrition, and Metabolism · PMID 33740389

RCT zitiert in: Glutathion (GSH)
2021 Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial

Del Prato S, Kahn SE, Pavo I, Weerakkody GJ, et al..The Lancet · PMID 34672967

RCT zitiert in: Tirzepatide
2021 Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes

Frías JP, Davies MJ, Rosenstock J, Pérez Manghi FC, et al..New England Journal of Medicine · PMID 34170647

RCT zitiert in: Tirzepatide
2020 A randomized crossover trial of elamipretide in adults with primary mitochondrial myopathy

Karaa A, Bertini E, Carelli V, et al..Journal of Cachexia, Sarcopenia and Muscle · PMID 32096613

RCT zitiert in: SS-31 (Elamipretide)
2020 EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease

Khavinson V, Linkova N, Kozhevnikova E, Trofimova S.Molecules · PMID 33396470

Übersicht zitiert in: Pinealon
2020 Melanotan II: a possible cause of renal infarction: review of the literature and case report

Peters B, Hadimeri H, Wahlberg R, Afghahi H.CEN Case Reports · PMID 31953620

Fallbericht zitiert in: Melanotan II
2020 Mitochondrial-derived peptides in energy metabolism

Merry TL, Chan A, Woodhead JST, et al..American Journal of Physiology. Endocrinology and Metabolism · PMID 32776825

Übersicht zitiert in: MOTS-c
2020 NAD+ homeostasis in health and disease

Katsyuba E, Romani M, Hofer D, Auwerx J.Nature Metabolism · PMID 32694684

Übersicht zitiert in: NAD+
2020 Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin-resistant men

Dollerup OL, Chubanava S, Agerholm M, et al..The Journal of Physiology · PMID 31710095

RCT zitiert in: NAD+
2020 NMR reveals an undeclared constituent in custom synthetic peptides

Choules MP, Bisson J, Simmler C, McAlpine JB, Giancaspro G, Bzhelyansky A, Niemitz M, Pauli GF.Journal of Pharmaceutical and Biomedical Analysis · PMID 31671336

SonstigesIn vitro zitiert in: DSIP,GLOW Blend,KLOW Blend,Pinealon
2020 PASylated Thymosin α1: A Long-Acting Immunostimulatory Peptide for Applications in Oncology and Virology

Binder U, Skerra A.International Journal of Molecular Sciences · PMID 33374407

Übersicht zitiert in: Thymosin Alpha-1
2020 Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

Covarrubias AJ, Kale A, Perrone R, et al..Nature Metabolism · PMID 33199924

Tier zitiert in: NAD+
2020 The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action

Mitchell W, Ng EA, Tamucci JD, et al..Journal of Biological Chemistry · PMID 32273339

In vitro zitiert in: SS-31 (Elamipretide)
2020 The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations

Vanhee C, Francotte A, Janvier S, Deconinck E.Drug Testing and Analysis · PMID 31667971

In vitroSonstiges zitiert in: GLOW Blend,N-Acetyl Semax,Selank
2019 A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD

Grant R, Berg J, Loake G, et al..Frontiers in Aging Neuroscience · PMID 31572171

Sonstiges zitiert in: NAD+
2019 Antioxidant supplementation for lung disease in cystic fibrosis

Ciofu O, Smith S, Lykkesfeldt J.Cochrane Database of Systematic Reviews · PMID 31580490

Meta zitiert in: Glutathion (GSH)
2019 Development of a mass spectrometry based detection method for the mitochondrion-derived peptide MOTS-c in plasma samples for doping control purposes

Knoop A, Thomas A, Thevis M.Rapid Communications in Mass Spectrometry · PMID 30394592

Sonstiges zitiert in: MOTS-c
2019 Effect of Peptide AEDG on Telomere Length and Mitotic Index of PHA-Stimulated Human Blood Lymphocytes

Khavinson VK, Pendina AA, Efimova OA, et al..Bulletin of Experimental Biology and Medicine · PMID 31761987

In vitro zitiert in: Epithalon
2019 Effects of elamipretide on skeletal muscle in dogs with experimentally induced heart failure

Sabbah HN, Gupta RC, Singh-Gupta V, et al..ESC Heart Failure · PMID 30688415

Tier zitiert in: SS-31 (Elamipretide)
2019 Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing

Gwyer D, Wragg NM, Wilson SL.Cell and Tissue Research · PMID 30915550

Übersicht zitiert in: BPC-157,BPC-157 + TB-500
2019 Genetic Nicotinamide N-Methyltransferase (Nnmt) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance

Brachs S, Polack J, Brachs M, Jahn-Hofmann K, et al..Diabetes · PMID 30552109

Tier zitiert in: 5-Amino-1MQ
2019 Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice

Campbell MD, Duan J, Samuelson AT, et al..Free Radical Biology and Medicine · PMID 30597195

Tier zitiert in: SS-31 (Elamipretide)
2019 Lipids and insulin regulate mitochondrial-derived peptide (MOTS-c) in PCOS and healthy subjects

Ramanjaneya M, Bettahi I, Jerobin J, et al..Clinical Endocrinology · PMID 31066084

Sonstiges zitiert in: MOTS-c
2019 Melanotan-induced priapism: a hard-earned tan

Dreyer BA, Amer T, Evans A, Reid H.BMJ Case Reports · PMID 30796078

Fallbericht zitiert in: Melanotan II
2019 Mitochondrial-Derived Peptides Are Down Regulated in Diabetes Subjects

Ramanjaneya M, Jerobin J, Bettahi I, et al..Frontiers in Endocrinology · PMID 31214116

Sonstiges zitiert in: MOTS-c
2019 Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease

Poole P, Sathananthan K, Fortescue R.Cochrane Database of Systematic Reviews · PMID 31107966

Meta zitiert in: Glutathion (GSH)
2019 Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

Elhassan YS, Kluckova K, Fletcher RS, et al..Cell Reports · PMID 31412242

RCT zitiert in: NAD+
2019 Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

Husain M, Birkenfeld AL, Donsmark M, Dungan K, et al..New England Journal of Medicine · PMID 31185157

RCT zitiert in: Semaglutide
2019 Safety of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283 and bioavailability of nicotinamide from this source, in the context of Directive 2002/46/EC

EFSA Panel on Nutrition, Novel Foods and Food Allergens.EFSA Journal · PMID 32626405

Behörde zitiert in: NAD+
2019 Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats.

Kolik LG, Nadorova AV, Antipova TA, et al..Bulletin of Experimental Biology and Medicine · PMID 31625062

Tier zitiert in: Selank
2019 The clinical effect of glutathione on skin color and other related skin conditions: A systematic review

Dilokthornsakul P, Dhippayom T, Dilokthornsakul W, et al..Journal of Cosmetic Dermatology · PMID 30895708

Meta zitiert in: Glutathion (GSH)
2019 The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivity

Kim SJ, Miller B, Mehta HH, et al..Physiological Reports · PMID 31293078

Tier zitiert in: MOTS-c
2018 A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects

Dollerup OL, Christensen B, Svart M, et al..The American Journal of Clinical Nutrition · PMID 29992272

RCT zitiert in: NAD+
2018 BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing

Seiwerth S, Milavic M, Vukojevic J, et al..Current Pharmaceutical Design · PMID 29998800

Übersicht zitiert in: BPC-157
2018 Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

Martens CR, Denman BA, Mazzo MR, et al..Nature Communications · PMID 29599478

RCT zitiert in: NAD+
2018 Mitochondrial-Derived Peptides Exacerbate Senescence

Mendelsohn AR, Larrick JW.Rejuvenation Research · PMID 30058454

Übersicht zitiert in: MOTS-c
2018 N-acetylcysteine supplementation increases exercise performance and reduces oxidative stress only in individuals with low levels of glutathione

Paschalis V, Theodorou AA, Margaritelis NV, et al..Free Radical Biology and Medicine · PMID 29233792

RCT zitiert in: Glutathion (GSH)
2018 NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR

Yoshino J, Baur JA, Imai S.Cell Metabolism · PMID 29249689

Übersicht zitiert in: NAD+
2018 Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function

Sinha R, Sinha I, Calcagnotto A, et al..European Journal of Clinical Nutrition · PMID 28853742

Sonstiges zitiert in: Glutathion (GSH)
2018 Plasma MOTS-c levels are associated with insulin sensitivity in lean but not in obese individuals

Bucci M, et al..Journal of Investigative Medicine · PMID 29593067

Sonstiges zitiert in: MOTS-c
2018 Randomized dose-escalation trial of elamipretide in adults with primary mitochondrial myopathy

Karaa A, Haas R, Goldstein A, et al..Neurology · PMID 29500292

RCT zitiert in: SS-31 (Elamipretide)
2018 Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data

Pickart L, Margolina A.International Journal of Molecular Sciences · PMID 29986520

Übersicht zitiert in: GHK-Cu
2018 Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Neelakantan H, Vance V, Wetzel MD, Wang HL, et al..Biochemical Pharmacology · PMID 29155147

Tier zitiert in: 5-Amino-1MQ
2018 The efficacy of semax in the treatment of patients at different stages of ischemic stroke

Gusev EI, Martynov MY, Kostenko EV, et al..Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova · PMID 29798983

Sonstiges zitiert in: Semax
2018 The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress

Kim KH, Son JM, Benayoun BA, et al..Cell Metabolism · PMID 29983246

In vitro zitiert in: MOTS-c
2017 Antioxidants for preventing and reducing muscle soreness after exercise

Ranchordas MK, Rogerson D, Soltani H, et al..Cochrane Database of Systematic Reviews · PMID 29238948

Meta zitiert in: Glutathion (GSH)
2017 Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study

Telomeres Mendelian Randomization Collaboration; Haycock PC, Burgess S, Nounu A, et al..JAMA Oncology · PMID 28241208

Meta zitiert in: Epithalon
2017 Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial

Sorli C, Harashima SI, Tsoukas GM, Unger J, et al..The Lancet Diabetes & Endocrinology · PMID 28110911

RCT zitiert in: Semaglutide
2017 GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells.

Filatova E, Kasian A, Kolomin T, et al..Frontiers in Pharmacology · PMID 28293190

In vitro zitiert in: Selank
2017 Glutathione and its antiaging and antimelanogenic effects

Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P.Clinical, Cosmetic and Investigational Dermatology · PMID 28490897

RCT zitiert in: Glutathion (GSH)
2017 NCT02914665: PROGRESS-HF, Elamipretide bei Herzinsuffizienz

ClinicalTrials.gov, Studienregistrierung

Datenbank zitiert in: SS-31 (Elamipretide)
2017 Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis

Xiao B, Xu Z, Viennois E, et al..Molecular Therapy · PMID 28143741

Tier zitiert in: KPV
2017 Risks of unregulated use of alpha-melanocyte-stimulating hormone analogues: a review

Habbema L, Halk AB, Neumann M, Bergman W.International Journal of Dermatology · PMID 28266027

Übersicht zitiert in: Melanotan II
2017 Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation

Hsieh MJ, Liu HT, Wang CN, et al..Journal of Molecular Medicine · PMID 27847966

In vitro zitiert in: BPC-157
2017 Transdermal Iontophoretic Delivery of Lysine-Proline-Valine (KPV) Peptide Across Microporated Human Skin

Pawar K, Kolli CS, Rangari VK, Babu RJ.Journal of Pharmaceutical Sciences · PMID 28343991

In vitro zitiert in: KPV
2016 A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study

Salvador L, Singaravelu G, Harley CB, et al..Rejuvenation Research · PMID 26950204

RCT zitiert in: Epithalon
2016 Amtliche Gebrauchsinformation Semax (Семакс), Nasentropfen 1 %, Registrierungsnummer Р N000812/01

Ministerium für Gesundheit der Russischen Föderation, veröffentlicht über medi.ru (Instruktion vom 26.08.2016)

Behörde zitiert in: Semax
2016 CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism

Camacho-Pereira J, Tarragó MG, Chini CCS, et al..Cell Metabolism · PMID 27304511

Tier zitiert in: NAD+
2016 Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure

Sabbah HN, Gupta RC, Kohli S, et al..Circulation: Heart Failure · PMID 26839394

Tier zitiert in: SS-31 (Elamipretide)
2016 Comparison of pharmacological effects of heptapeptide selank after intranasal and intraperitoneal administration to BALB/c and C57BL/6 mice

Vasil'eva EV, Kondrakhin EA, Salimov RM, Kovalev GI.Eksperimental'naia i Klinicheskaia Farmakologiia · PMID 29787664

Tier zitiert in: Selank
2016 Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic

Moskalev A, Chernyagina E, Tsvetkov V, et al..Aging Cell · PMID 26970234

Übersicht zitiert in: Epithalon
2016 EMBRACE STEMI study: a Phase 2a trial to evaluate the safety, tolerability, and efficacy of intravenous MTP-131 on reperfusion injury in patients undergoing primary percutaneous coronary intervention

Gibson CM, Giugliano RP, Kloner RA, et al..European Heart Journal · PMID 26586786

RCT zitiert in: SS-31 (Elamipretide)
2016 Influence of the N-terminus acetylation of Semax, a synthetic analog of ACTH(4-10), on copper(II) and zinc(II) coordination and biological properties.

Magrì A, Tabbì G, Giuffrida A, et al..Journal of Inorganic Biochemistry · PMID 27586814

In vitro zitiert in: N-Acetyl Semax
2016 Intravenous glutathione for skin lightening: Inadequate safety data

Davids LM, Van Wyk JC, Khumalo NP.South African Medical Journal · PMID 27499402

Übersicht zitiert in: Glutathion (GSH)
2016 ISO 8537: Sterile single-use syringes, with or without needle, for insulin

International Organization for Standardization

Behörde zitiert in: Insulinspritzen
2016 Physicochemical characterization of native glycyl-l-histidyl-l-lysine tripeptide for wound healing and anti-aging: a preformulation study for dermal delivery

Badenhorst T, Svirskis D, Wu Z.Pharmaceutical Development and Technology · PMID 25384620

In vitro zitiert in: AHK-Cu,GHK-Cu,GLOW Blend,KLOW Blend
2016 Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

Marso SP, Bain SC, Consoli A, Eliaschewitz FG, et al..New England Journal of Medicine · PMID 27633186

RCT zitiert in: Semaglutide
2016 The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice

Park JR, Lee H, Kim SI, Yang SR.Oncotarget · PMID 27517151

Tier zitiert in: GHK-Cu
2016 Thymosin β4 Promotes Dermal Healing

Kleinman HK, Sosne G.Vitamins and Hormones · PMID 27450738

Übersicht zitiert in: TB-500
2016 WHO guideline on the use of safety-engineered syringes for intramuscular, intradermal and subcutaneous injections

World Health Organization

Leitlinie zitiert in: Bakteriostatisches Wasser,Insulinspritzen
2015 Afamelanotide for Erythropoietic Protoporphyria

Langendonk JG, Balwani M, Anderson KE, et al..New England Journal of Medicine · PMID 26132941

RCT zitiert in: Melanotan II
2015 Amylin: Pharmacology, Physiology, and Clinical Potential

Hay DL, Chen S, Lutz TA, Parkes DG, et al..Pharmacological Reviews · PMID 26071095

Übersicht zitiert in: Cagrilintide
2015 Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

Kannt A, Pfenninger A, Teichert L, Tönjes A, et al..Diabetologia · PMID 25596852

Sonstiges zitiert in: 5-Amino-1MQ
2015 Detection and in vitro metabolism of AOD9604

Cox HD, Smeal SJ, Hughes CM, Cox JE, et al..Drug Testing and Analysis · PMID 25208511

In vitro zitiert in: AOD-9604
2015 Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model

Kwon DR, Park GY.Annals of Clinical and Laboratory Science · PMID 26275694

Tier zitiert in: AOD-9604
2015 Effect of synthetic peptides on aging of patients with chronic polymorbidity and organic brain syndrome of the central nervous system in remission

Meshchaninov VN, Tkachenko EL, Zharkov SV, Gavrilov IV, Katyreva IuE.Advances in Gerontology (Adv Gerontol) · PMID 26390612

Sonstiges zitiert in: Pinealon
2015 Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet

Breindahl T, Evans-Brown M, Hindersson P, McVeigh J, Bellis M, Stensballe A, Kimergård A.Drug Testing and Analysis · PMID 24771717

In vitro zitiert in: GLOW Blend,KLOW Blend,Melanotan II
2015 Identification of the small research tetra peptide Epitalon, assumed to be a potential treatment for cancer, old age and Retinitis Pigmentosa in two illegal pharmaceutical preparations

Vanhee C, Moens G, Van Hoeck E, et al..Drug Testing and Analysis · PMID 25535022

Behörde zitiert in: Epithalon
2015 Microneedle-Mediated Delivery of Copper Peptide Through Skin

Li H, Low YS, Chong HP, et al..Pharmaceutical Research · PMID 25690343

In vitro zitiert in: AHK-Cu,GHK-Cu,GLOW Blend
2015 NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Cantó C, Menzies KJ, Auwerx J.Cell Metabolism · PMID 26118927

Übersicht zitiert in: NAD+
2015 Randomized controlled trial of oral glutathione supplementation on body stores of glutathione

Richie JP Jr, Nichenametla S, Neidig W, et al..European Journal of Nutrition · PMID 24791752

RCT zitiert in: Glutathion (GSH)
2015 The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Lee C, Zeng J, Drew BG, et al..Cell Metabolism · PMID 25738459

Tier zitiert in: MOTS-c
2014 BPC 157 and blood vessels

Seiwerth S, Brcic L, Vuletic LB, et al..Current Pharmaceutical Design · PMID 23782145

Übersicht zitiert in: BPC-157
2014 Identification and characterization of peptide drugs in unknown pharmaceutical preparations seized by the Belgian authorities: case report on AOD9604

Vanhee C, Moens G, Deconinck E, De Beer JO.Drug Testing and Analysis · PMID 24976118

Fallbericht zitiert in: AOD-9604
2014 Melanoma associated with the use of melanotan-II

Hjuler KF, Lorentzen HF.Dermatology · PMID 24355990

Fallbericht zitiert in: Melanotan II
2014 NAD+ and sirtuins in aging and disease

Imai S, Guarente L.Trends in Cell Biology · PMID 24786309

Übersicht zitiert in: NAD+
2014 NCT01280344: Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal Function

ClinicalTrials.gov, U.S. National Library of Medicine

Datenbank zitiert in: Ipamorelin
2014 Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

Kraus D, Yang Q, Kong D, Banks AS, et al..Nature · PMID 24717514

Tier zitiert in: 5-Amino-1MQ
2014 Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients

Beck DE, Sweeney WB, McCarter MD.International Journal of Colorectal Disease · PMID 25331030

RCT zitiert in: CJC-1295 + Ipamorelin,Ipamorelin,Tesamorelin + Ipamorelin
2014 Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis

Birk AV, Chao WM, Bracken C, Warren JD, Szeto HH.British Journal of Pharmacology · PMID 24134698

In vitro zitiert in: SS-31 (Elamipretide)
2013 Determination That GEREF (Sermorelin Acetate) Injection, 0.5 Milligrams Base/Vial and 1.0 Milligrams Base/Vial, Were Not Withdrawn From Sale for Reasons of Safety or Effectiveness

Federal Register, 78 FR 14095, 4. März 2013

Behörde zitiert in: Sermorelin
2013 Effect of peptide geroprotectors on the navigation system learning and caspase-3 in brain structures in rats of different age

Mendzheritski AM, Karantysh GV, Abramchuk VA, Ryzhak GA.Advances in Gerontology (Adv Gerontol) · PMID 28976148

Tier zitiert in: Pinealon
2013 Melanotan II overdose associated with priapism

Devlin J, Pomerleau A, Myers B, et al..Clinical Toxicology · PMID 23537392

Fallbericht zitiert in: Melanotan II
2013 Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice

Siegel MP, Kruse SE, Percival JM, et al..Aging Cell · PMID 23692570

Tier zitiert in: SS-31 (Elamipretide)
2013 Stability of Semax acetyl to proteolysis in various biological media.

Shevchenko KV, Nagaev IY, Andreeva LA, et al..Doklady Biological Sciences · PMID 23652441

In vitro zitiert in: N-Acetyl Semax
2013 The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial

Wu J, Zhou L, Liu J, et al..Critical Care · PMID 23327199

RCT zitiert in: Thymosin Alpha-1
2013 The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin

Birk AV, Liu S, Soong Y, et al..Journal of the American Society of Nephrology · PMID 23813215

In vitro zitiert in: SS-31 (Elamipretide)
2012 Age-associated changes in oxidative stress and NAD+ metabolism in human tissue

Massudi H, Grant R, Braidy N, Guest J, Farnsworth B, Guillemin GJ.PLoS ONE · PMID 22848760

Sonstiges zitiert in: NAD+
2012 Analysis of some parameters of biological age and adaptation possibilities of workers of locomotive brigades

Nazimko VA, Morgul EV, Petrova OA, Sheikhova RG, Kozina LS, Savenko MA, Lysenko DS.Advances in Gerontology (Adv Gerontol) · PMID 22708445

Sonstiges zitiert in: Pinealon
2012 Doping control analysis of TB-500, a synthetic version of an active region of thymosin β4, in equine urine and plasma by liquid chromatography-mass spectrometry

Ho EN, Kwok WH, Lau MY, et al..Journal of Chromatography A · PMID 23084823

Tier zitiert in: BPC-157 + TB-500,TB-500
2012 Focus on ulcerative colitis: stable gastric pentadecapeptide BPC 157

Sikiric P, Seiwerth S, Rucman R, et al..Current Medicinal Chemistry · PMID 22300085

Übersicht zitiert in: BPC-157
2012 Infusion with the antioxidant N-acetylcysteine attenuates early adaptive responses to exercise in human skeletal muscle

Petersen AC, McKenna MJ, Medved I, et al..Acta Physiologica · PMID 21827635

RCT zitiert in: Glutathion (GSH)
2012 Melanotan II injection resulting in systemic toxicity and rhabdomyolysis

Nelson ME, Bryant SM, Aks SE.Clinical Toxicology · PMID 23121206

Fallbericht zitiert in: Melanotan II
2012 Melanotan-associated melanoma in situ

Ong S, Bowling J.Australasian Journal of Dermatology · PMID 22724573

Fallbericht zitiert in: Melanotan II
2012 Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial

Makimura H, Feldpausch MN, Rope AM, Hemphill LC, Torriani M, Lee H, Grinspoon SK.The Journal of Clinical Endocrinology and Metabolism · PMID 23015655

RCT zitiert in: Tesamorelin
2012 N-acetylcysteine for sepsis and systemic inflammatory response in adults

Szakmany T, Hauser B, Radermacher P.Cochrane Database of Systematic Reviews · PMID 22972094

Meta zitiert in: Glutathion (GSH)
2012 Questions and answers: Withdrawal of the marketing authorisation application for Egrifta (tesamorelin), EMA/CHMP/475021/2012, Verfahren EMEA/H/C/002427

European Medicines Agency

Behörde zitiert in: Tesamorelin,Tesamorelin + Ipamorelin
2012 Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin

Stanley TL, Falutz J, Marsolais C, Morin J, Soulban G, Mamputu JC, Assaad H, Turner R, Grinspoon SK.Clinical Infectious Diseases · PMID 22495074

Sonstiges zitiert in: Tesamorelin
2012 Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential

Esposito S, Deventer K, Van Eenoo P.Drug Testing and Analysis · PMID 22962027

In vitro zitiert in: GLOW Blend
2012 The Human Medicines Regulations 2012 (SI 2012/1916), Regulation 46: Requirement for authorisation

UK Government.legislation.gov.uk

Behörde zitiert in: Melanotan II
2011 C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus

Singh M, Mukhopadhyay K.Antimicrobial Agents and Chemotherapy · PMID 21282427

In vitro zitiert in: KPV
2011 Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

Sekhar RV, Patel SG, Guthikonda AP, et al..The American Journal of Clinical Nutrition · PMID 21795440

RCT zitiert in: Glutathion (GSH)
2011 Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers

Allen J, Bradley RD.Journal of Alternative and Complementary Medicine · PMID 21875351

RCT zitiert in: Glutathion (GSH)
2011 Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine

Sekhar RV, McKay SV, Patel SG, et al..Diabetes Care · PMID 20929994

RCT zitiert in: Glutathion (GSH)
2011 Human skin penetration of a copper tripeptide in vitro as a function of skin layer

Hostynek JJ, Dreher F, Maibach HI.Inflammation Research · PMID 20721598

In vitro zitiert in: AHK-Cu,GHK-Cu
2011 Melanotan-associated melanoma

Paurobally D, Jason F, Dezfoulian B, Nikkels AF.British Journal of Dermatology · PMID 21564053

Fallbericht zitiert in: Melanotan II
2011 Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA

Fedoreyeva LI, Kireev II, Khavinson VKh, Vanyushin BF.Biochemistry (Moscow) · PMID 22117547

In vitro zitiert in: Pinealon
2011 Peptide geroprotector from the pituitary gland inhibits rapid aging of elderly people: results of 15-year follow-up

Korkushko OV, Khavinson VKh, Shatilo VB, Antonyk-Sheglova IA.Bulletin of Experimental Biology and Medicine · PMID 22451889

RCT zitiert in: Epithalon
2011 Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes

Khavinson V, Ribakova Y, Kulebiakin K, Vladychenskaya E, Kozina L, Arutjunyan A, Boldyrev A.Rejuvenation Research · PMID 21978084

In vitro zitiert in: Pinealon
2010 A randomized, placebo-controlled, single and multiple dose study of intravenous thymosin beta4 in healthy volunteers

Ruff D, Crockford D, Girardi G, et al..Annals of the New York Academy of Sciences · PMID 20536472

RCT zitiert in: TB-500
2010 BfArM warnt vor Anwendung melanotanhaltiger Produkte für kosmetische Zwecke (Pressemitteilung 14/10 vom 28.10.2010)

Bundesinstitut für Arzneimittel und Medizinprodukte.BfArM

Behörde zitiert in: Melanotan II
2010 Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data

Falutz J, Mamputu JC, Potvin D, Moyle G, Soulban G, Loughrey H, Marsolais C, Turner R, Grinspoon S.The Journal of Clinical Endocrinology and Metabolism · PMID 20554713

MetaRCT zitiert in: Tesamorelin,Tesamorelin + Ipamorelin
2010 Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: a randomized placebo-controlled trial with a safety extension

Falutz J, Potvin D, Mamputu JC, Assaad H, Zoltowska M, Michaud SE, Berger D, Somero M, Moyle G, Brown S, Martorell C, Turner R, Grinspoon S.Journal of Acquired Immune Deficiency Syndromes · PMID 20101189

RCT zitiert in: Tesamorelin
2010 Reply: Based on the available randomized trial patients should say no to glutathione for Parkinson disease

Okun MS, Lang A, Jankovic J.Movement Disorders · PMID 20461816

Sonstiges zitiert in: Glutathion (GSH)
2010 Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia.

Dmitrieva VG, Povarova OV, Skvortsova VI, et al..Cellular and Molecular Neurobiology · PMID 19633950

Tier zitiert in: Semax
2010 WHO best practices for injections and related procedures toolkit

World Health Organization

Leitlinie zitiert in: Alkoholtupfer,Bakteriostatisches Wasser,Insulinspritzen
2009 alpha-Melanocyte-stimulating hormone-induced eruptive nevi

Cardones AR, Grichnik JM.Archives of Dermatology · PMID 19380666

Fallbericht zitiert in: Melanotan II
2009 Antioxidants prevent health-promoting effects of physical exercise in humans

Ristow M, Zarse K, Oberbach A, et al..Proceedings of the National Academy of Sciences · PMID 19433800

RCT zitiert in: Glutathion (GSH)
2009 Determinants of GH-releasing hormone and GH-releasing peptide synergy in men

Veldhuis JD, Bowers CY.American Journal of Physiology, Endocrinology and Metabolism · PMID 19240251

Sonstiges zitiert in: CJC-1295 + Ipamorelin,Tesamorelin + Ipamorelin
2009 Novartis Pharmaceuticals Corp. et al.; Withdrawal of Approval of 92 New Drug Applications and 49 Abbreviated New Drug Applications

Federal Register, 74 FR 23407, 19. Mai 2009

Behörde zitiert in: Sermorelin
2009 Randomized, double-blind, pilot evaluation of intravenous glutathione in Parkinson disease

Hauser RA, Lyons KE, McClain T, Carter J, Perlmutter D.Movement Disorders · PMID 19230029

RCT zitiert in: Glutathion (GSH)
2009 Verordnung (EG) Nr. 1223/2009 über kosmetische Mittel

Europäisches Parlament und Rat.EUR-Lex

Behörde zitiert in: AHK-Cu,GHK-Cu,Melanotan II
2008 Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases

Brzoska T, Luger TA, Maaser C, et al..Endocrine Reviews · PMID 18612139

Übersicht zitiert in: KPV
2008 Anti-microbial action of melanocortin peptides and identification of a novel X-Pro-D/L-Val sequence in Gram-positive and Gram-negative bacteria

Charnley M, Moir AJ, Douglas CW, Haycock JW.Peptides · PMID 18355945

In vitro zitiert in: KPV
2008 Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia

Zozulia AA, Neznamov GG, Siuniakov TS, et al..Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova · PMID 18454096

Sonstiges zitiert in: Selank
2008 Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men

Paulo RC, Cosma M, So R, et al..The Journal of Clinical Endocrinology & Metabolism · PMID 18073313

Sonstiges zitiert in: CJC-1295 + Ipamorelin
2008 Immunomodulatory effects of selank in patients with anxiety-asthenic disorders

Uchakina ON, Uchakin PN, Miasoedov NF, et al..Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova · PMID 18577961

Sonstiges zitiert in: Selank
2008 Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease

Kannengiesser K, Maaser C, Heidemann J, et al..Inflammatory Bowel Diseases · PMID 18092346

Tier zitiert in: GLOW Blend,KLOW Blend,KPV
2008 Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance

Gomez-Cabrera MC, Domenech E, Romagnoli M, et al..The American Journal of Clinical Nutrition · PMID 18175748

RCT zitiert in: Glutathion (GSH)
2008 PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation

Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al..Gastroenterology · PMID 18061177

Tier zitiert in: KLOW Blend
2007 Metabolic effects of a growth hormone-releasing factor in patients with HIV

Falutz J, Allas S, Blot K, Potvin D, Kotler D, Somero M, Berger D, Brown S, Richmond G, Fessel J, Turner R, Grinspoon S.The New England Journal of Medicine · PMID 18057338

RCT zitiert in: Tesamorelin,Tesamorelin + Ipamorelin
2007 Potent mitochondria-targeted peptides reduce myocardial infarction in rats

Cho J, Won K, Wu D, et al..Coronary Artery Disease · PMID 17429296

Tier zitiert in: SS-31 (Elamipretide)
2007 The effect of tripeptide-copper complex on human hair growth in vitro

Pyo HK, Yoo HG, Won CH, Lee SH, Kang YJ, Eun HC, Cho KH, Kim KH.Archives of Pharmacal Research · PMID 17703734

In vitro zitiert in: AHK-Cu
2006 Delta sleep-inducing peptide (DSIP): a still unresolved riddle

Kovalzon VM, Strekalova TV.Journal of Neurochemistry · PMID 16539679

Übersicht zitiert in: DSIP
2006 Evaluation of the effects of topical tripeptide-copper complex and zinc oxide on open-wound healing in rabbits

Cangul IT, Gul NY, Topal A, Yilmaz R.Veterinary Dermatology · PMID 17083573

Tier zitiert in: GHK-Cu
2006 NCT00267527: A Study to Evaluate CJC 1295 in HIV Patients With Visceral Obesity

ClinicalTrials.gov, U.S. National Library of Medicine

Datenbank zitiert in: CJC-1295 (No DAC)
2006 Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults

Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA.The Journal of Clinical Endocrinology and Metabolism · PMID 16352683

RCT zitiert in: CJC-1295 (No DAC),CJC-1295 + Ipamorelin
2006 Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog

Ionescu M, Frohman LA.The Journal of Clinical Endocrinology and Metabolism · PMID 17018654

Sonstiges zitiert in: CJC-1295 (No DAC)
2006 Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus.

Dolotov OV, Karpenko EA, Inozemtseva LS, et al..Brain Research · PMID 16996037

Tier zitiert in: Semax
2006 Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain.

Dolotov OV, Karpenko EA, Seredenina TS, et al..Journal of Neurochemistry · PMID 16635254

Tier zitiert in: Semax
2005 Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog

Jetté L, Léger R, Thibaudeau K, Benquet C, Robitaille M, Pellerin I, Paradis V, van Wyk P, Pham K, Bridon DP.Endocrinology · PMID 15817669

Tier zitiert in: CJC-1295 (No DAC),CJC-1295 + Ipamorelin
2004 AOD-9604 Metabolic

Wilding J.Current Opinion in Investigational Drugs · PMID 15134286

Übersicht zitiert in: AOD-9604
2004 Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury

Zhao K, Zhao GM, Wu D, Soong Y, Birk AV, Schiller PW, Szeto HH.Journal of Biological Chemistry · PMID 15178689

In vitro zitiert in: SS-31 (Elamipretide)
2004 Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers

Dorr RT, Ertl G, Levine N, et al..Archives of Dermatology · PMID 15262693

RCT zitiert in: Melanotan II
2004 N-acetylcysteine enhances muscle cysteine and glutathione availability and attenuates fatigue during prolonged exercise in endurance-trained individuals

Medved I, Brown MJ, Bjorksten AR, et al..Journal of Applied Physiology · PMID 15194675

RCT zitiert in: Glutathion (GSH)
2004 Peptide promotes overcoming of the division limit in human somatic cell

Khavinson VKh, Bondarev IE, Butyugov AA, Smirnova TD.Bulletin of Experimental Biology and Medicine · PMID 15455129

In vitro zitiert in: Epithalon
2004 The binding of Semax, ACTH 4-10 heptapeptide, to plasma membranes of the rat forebrain basal nuclei and its biodegradation

Dolotov OV, Zolotarev YA, Dorokhova EM, et al..Bioorganicheskaia Khimiia (Russian Journal of Bioorganic Chemistry) · PMID 15344653

Tier zitiert in: N-Acetyl Semax
2003 Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides

Getting SJ, Schiöth HB, Perretti M.Journal of Pharmacology and Experimental Therapeutics · PMID 12750433

Tier zitiert in: KLOW Blend,KPV
2003 Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice

Anisimov VN, Khavinson VKh, Popovich IG, et al..Biogerontology · PMID 14501183

Tier zitiert in: Epithalon
2003 Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells

Khavinson VKh, Bondarev IE, Butyugov AA.Bulletin of Experimental Biology and Medicine · PMID 12937682

In vitro zitiert in: Epithalon
2003 N-acetylcysteine infusion alters blood redox status but not time to fatigue during intense exercise in humans

Medved I, Brown MJ, Bjorksten AR, McKenna MJ.Journal of Applied Physiology · PMID 12496140

RCT zitiert in: Glutathion (GSH)
2003 PEGylation of growth hormone-releasing hormone (GRF) analogues

Esposito P, Barbero L, Caccia P, Caliceti P, D’Antonio M, Piquet G, Veronese FM.Advanced Drug Delivery Reviews · PMID 14499707

Übersicht zitiert in: CJC-1295 (No DAC),Sermorelin
2003 Peptides of pineal gland and thymus prolong human life

Khavinson VKh, Morozov VG.Neuroendocrinology Letters · PMID 14523363

Sonstiges zitiert in: Epithalon
2003 The effectiveness of arginine + GHRH test compared with GHRH + GHRP-6 test in diagnosing growth hormone deficiency in adults

Popovic V, Pekic S, Doknic M, et al..Clinical Endocrinology · PMID 12864804

Sonstiges zitiert in: CJC-1295 + Ipamorelin
2003 Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice

Philp D, Badamchian M, Scheremeta B, et al..Wound Repair and Regeneration · PMID 12581423

Tier zitiert in: TB-500
2002 Copper-induced vascular endothelial growth factor expression and wound healing

Sen CK, Khanna S, Venojarvi M, et al..American Journal of Physiology, Heart and Circulatory Physiology · PMID 11959648

Tier zitiert in: GHK-Cu
2002 Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/neu transgenic mice

Anisimov VN, Khavinson VK, Provinciali M, et al..International Journal of Cancer · PMID 12209581

Tier zitiert in: Epithalon
2001 Delta sleep-inducing peptide

Pollard BJ, Pomfrett CJ.European Journal of Anaesthesiology · PMID 11437870

Übersicht zitiert in: DSIP
2001 Effects of melanocortin peptides on lipopolysaccharide/interferon-gamma-induced NF-kappaB DNA binding and nitric oxide production in macrophage-like RAW 264.7 cells: evidence for dual mechanisms of action

Mandrika I, Muceniece R, Wikberg JE.Biochemical Pharmacology · PMID 11239505

In vitro zitiert in: KPV
2001 Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment

Heffernan MA, Thorburn AW, Fam B, Summers R, et al..International Journal of Obesity and Related Metabolic Disorders · PMID 11673763

Tier zitiert in: AOD-9604
2001 Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes

González-Suárez E, Samper E, Ramírez A, et al..The EMBO Journal · PMID 11387197

Tier zitiert in: Epithalon
2001 Richtlinie 2001/83/EG zur Schaffung eines Gemeinschaftskodexes für Humanarzneimittel

Europäisches Parlament und Rat.EUR-Lex

Behörde zitiert in: AHK-Cu,BPC-157,BPC-157 + TB-500,CJC-1295 (No DAC),CJC-1295 + Ipamorelin,DSIP,Epithalon,GHK-Cu,GLOW Blend,Glutathion (GSH),Ipamorelin,KLOW Blend,KPV,Melanotan II,MOTS-c,N-Acetyl Semax,NAD+,Pinealon,Selank,Semax,Sermorelin,SS-31 (Elamipretide),TB-500,Tesamorelin,Tesamorelin + Ipamorelin,Thymosin Alpha-1,Tripple-G
2001 The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice

Heffernan M, Summers RJ, Thorburn A, Ogru E, et al..Endocrinology · PMID 11713213

Tier zitiert in: AOD-9604
2000 Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone

Ng FM, Sun J, Sharma L, Libinaka R, et al..Hormone Research · PMID 11146367

Tier zitiert in: AOD-9604
1999 Glutathione and its role in cellular functions

Sies H.Free Radical Biology and Medicine · PMID 10569624

Übersicht zitiert in: Glutathion (GSH)
1999 Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers

Gobburu JV, Agersø H, Jusko WJ, Ynddal L.Pharmaceutical Research · PMID 10496658

Sonstiges zitiert in: CJC-1295 + Ipamorelin,Ipamorelin,Tesamorelin + Ipamorelin
1999 Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency

Prakash A, Goa KL.BioDrugs 12(2):139-57 · PMID 18031173

Übersicht zitiert in: Sermorelin
1998 Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation

Pandya N, DeMott-Friberg R, Bowers CY, Barkan AL, Jaffe CA.The Journal of Clinical Endocrinology & Metabolism · PMID 9543138

Sonstiges zitiert in: CJC-1295 + Ipamorelin
1998 Ipamorelin, the first selective growth hormone secretagogue

Raun K, Hansen BS, Johansen NL, et al..European Journal of Endocrinology · PMID 9849822

Tier zitiert in: CJC-1295 + Ipamorelin,Ipamorelin,Tesamorelin + Ipamorelin
1997 Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: results of a double-blind, randomised trial

Smyth JF, Bowman A, Perren T, et al..Annals of Oncology · PMID 9261526

RCT zitiert in: Glutathion (GSH)
1996 Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study

Dorr RT, Lines R, Levine N, Brooks C, Xiang L, Hruby VJ, Hadley ME.Life Sciences · PMID 8637402

RCT zitiert in: Melanotan II
1996 Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy

Thorner M, Rochiccioli P, Colle M, Lanes R, et al. (Geref International Study Group).Journal of Clinical Endocrinology and Metabolism 81(3):1189-96 · PMID 8772599

Sonstiges zitiert in: Sermorelin
1996 Reduced intravenous glutathione in the treatment of early Parkinson disease

Sechi G, Deledda MG, Bua G, et al..Progress in Neuro-Psychopharmacology and Biological Psychiatry · PMID 8938817

Sonstiges zitiert in: Glutathion (GSH)
1995 Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: a randomized double-blind placebo-controlled trial

Cascinu S, Cordella L, Del Ferro E, et al..Journal of Clinical Oncology · PMID 7799029

RCT zitiert in: Glutathion (GSH)
1994 Binding of anti-inflammatory alpha-melanocyte-stimulating-hormone peptides and proinflammatory cytokines to receptors on melanoma cells

Lyson K, Ceriani G, Takashima A, et al..Neuroimmunomodulation · PMID 7489322

In vitro zitiert in: KPV
1994 Specific association of human telomerase activity with immortal cells and cancer

Kim NW, Piatyszek MA, Prowse KR, et al..Science · PMID 7605428

Tier zitiert in: Epithalon
1994 Treatment with GHRH(1-29)NH2 in children with idiopathic short stature induces a sustained increase in growth velocity

Kirk JM, Trainer PJ, Majrowski WH, Murphy J, et al..Clinical Endocrinology (Oxford) 41(4):487-93 · PMID 7955460

Sonstiges zitiert in: Sermorelin
1994 Приказ Минздравмедпрома РФ от 20.12.1994 N 294 „О разрешении к медицинскому применению“ (Anordnung Nr. 294 des Ministeriums für Gesundheit und Medizinindustrie der Russischen Föderation)

Ministerium für Gesundheit und Medizinindustrie der Russischen Föderation

Behörde zitiert in: Semax
1993 Degradation of ACTH/MSH(4-10) and its synthetic analog semax by rat serum enzymes: an inhibitor study.

Potaman VN, Alfeeva LY, Kamensky AA, et al..Peptides · PMID 8392718

Tier zitiert in: N-Acetyl Semax
1993 In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds

Maquart FX, Bellon G, Chaqour B, et al..Journal of Clinical Investigation · PMID 8227353

Tier zitiert in: GHK-Cu,GLOW Blend,KLOW Blend
1992 Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men

Corpas E, Harman SM, Piñeyro MA, Roberson R, Blackman MR.Journal of Clinical Endocrinology and Metabolism 75(2):530-5 · PMID 1379256

RCT zitiert in: Sermorelin
1992 The systemic availability of oral glutathione

Witschi A, Reddy S, Stofer B, Lauterburg BH.European Journal of Clinical Pharmacology · PMID 1362956

RCT zitiert in: Glutathion (GSH)
1991 N-terminal degradation of ACTH(4-10) and its synthetic analog semax by the rat blood enzymes.

Potaman VN, Alfeeva LY, Kamensky AA, et al..Biochemical and Biophysical Research Communications · PMID 1851003

Tier zitiert in: N-Acetyl Semax,Semax
1988 Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-l-lysine-Cu2+

Maquart FX, Pickart L, Laurent M, Gillery P, Monboisse JC, Borel JP.FEBS Letters · PMID 3169264

In vitro zitiert in: GHK-Cu,GLOW Blend,KLOW Blend
1987 Study of delta sleep-inducing peptide efficacy in improving sleep on short-term administration to chronic insomniacs

Monti JM, Debellis J, Alterwain P, Pellejero T, Monti D.International Journal of Clinical Pharmacology Research · PMID 3583493

RCT zitiert in: DSIP
1987 Treatment of growth-hormone deficiency with growth-hormone-releasing hormone

Ross RJ, Rodda C, Tsagarakis S, Davies PS, et al..The Lancet 1(8523):5-8 · PMID 2879138

Sonstiges zitiert in: Sermorelin
1986 Delta-sleep-inducing peptide (DSIP): an update

Graf MV, Kastin AJ.Peptides · PMID 3550726

Übersicht zitiert in: DSIP
1984 Characterization, properties and multivariate functions of delta-sleep-inducing peptide (DSIP)

Schoenenberger GA.European Neurology · PMID 6548966

Übersicht zitiert in: DSIP
1984 Delta-sleep-inducing peptide (DSIP): a review

Graf MV, Kastin AJ.Neuroscience and Biobehavioral Reviews · PMID 6145137

Übersicht zitiert in: DSIP
1984 Presence of delta-sleep-inducing peptide-like material in human milk

Graf MV, Hunter CA, Kastin AJ.The Journal of Clinical Endocrinology and Metabolism · PMID 6547144

Sonstiges zitiert in: DSIP
1982 The gasping syndrome and benzyl alcohol poisoning

Gershanik JJ, Boecler B, Ensley H, McCloskey S, George W.New England Journal of Medicine

Fallbericht zitiert in: Bakteriostatisches Wasser
1981 The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep

Schneider-Helmert D, Schoenenberger GA.Experientia · PMID 7028502

Sonstiges zitiert in: DSIP
1977 Characterization of a delta-electroencephalogram (-sleep)-inducing peptide

Schoenenberger GA, Monnier M.Proceedings of the National Academy of Sciences of the USA · PMID 265572

Tier zitiert in: DSIP

Alle Angaben mit PMID oder DOI werden maschinell gegen PubMed und Crossref geprüft. Quellen der Art „Erfahrungsbericht" sind im jeweiligen Beitrag sichtbar gekennzeichnet und dienen nie als Wirkbeleg. Der Prüflauf ist Teil der Prüfkette, Details stehen unter Methodik.